Index: lib_pypy/_cffi_ssl/_cffi_src/openssl/x509.py
--- lib_pypy/_cffi_ssl/_cffi_src/openssl/x509.py.orig
+++ lib_pypy/_cffi_ssl/_cffi_src/openssl/x509.py
@@ -282,7 +282,7 @@ int X509_get_signature_nid(const X509 *x)
 
 /* Added in 1.0.2 but we need it in all versions now due to the great
    opaquing. */
-#if CRYPTOGRAPHY_OPENSSL_LESS_THAN_102
+#if CRYPTOGRAPHY_OPENSSL_LESS_THAN_102 && !defined(LIBRESSL_VERSION_NUMBER)
 /* from x509/x_x509.c */
 int i2d_re_X509_tbs(X509 *x, unsigned char **pp)
 {
@@ -308,7 +308,7 @@ X509_REVOKED *Cryptography_X509_REVOKED_dup(X509_REVOK
 
 /* Added in 1.1.0 but we need it in all versions now due to the great
    opaquing. */
-#if CRYPTOGRAPHY_OPENSSL_LESS_THAN_110
+#if CRYPTOGRAPHY_OPENSSL_LESS_THAN_110 && !defined(LIBRESSL_VERSION_NUMBER)
 int i2d_re_X509_REQ_tbs(X509_REQ *req, unsigned char **pp)
 {
     req->req_info->enc.modified = 1;